Advancing the Science of Precision Immunotherapy

Our research forms the cornerstone of our innovative approach. MabQuest Therapeutics is committed to advancing the science behind innovative immunotherapy approaches, and our publications reflect our dedication to rigorous research and clinical excellence.

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Journal of Experimental Medicine

Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway

2019

Oncology
Frontiers in Immunology

A CD64/FcgammaRI-mediated mechanism hijacks PD-1 from PD-L1/2 interaction and enhances anti-PD-1 functional recovery of exhausted T cells

2023

Immunology
Immunological Reviews

T-cell exhaustion in HIV infection

2019

Oncology
Immunology
Nature Microbiology

Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys

2022

Infectious Disease
Infectious Diseases and Therapy

A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutralization Profile of Two Investigational Long-Acting Anti-SARS-CoV-2 Monoclonal Antibodies

2024

Infectious Disease
Journal of Thoracic Oncology

Personalized Cytokine-Directed Therapy With Tocilizumab for Refractory Immune Checkpoint Inhibitor-Related Cholangiohepatitis

2021

Oncology
Journal of Infection

Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys

2023

Infectious Disease
Cell Reports

A highly potent antibody effective against SARS-CoV-2 variants of concern

2023

Infectious Disease
Cell Host & Microbe

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01

2019

Infectious Disease
Journal of Clinical Oncology

Identification of novel antagonistic anti-PD-1 antibodies that are non-blocking of the PD-1/PD-L1 interaction

2016

Oncology
Immunology